Tiroid Nodüllerinin Değerlendirilmesinde Bethesda Sistemi ve İnce İğne Aspirasyon Biopsisinin Yeri

Aim: In this study, the role of fine needle aspiration biopsy (FNAB) evaluated with Bethesda System in diagnosis thyroid nodules was investigated. Materials and Methods: Total 2284 FNAB materials 1846 patients were performed Pathology Department Kutahya Health Sciences University, Evliya Celebi Traning Research Hospital between 2016 2019 reported according to category. Among these cases, diagnostic sensitivity, specificity, accuracy, positive negative predictive values calculated by making cytohistopathologica comparison 328 cases who underwent total thyroidectomy. Results: 1538 included female (83.31%) 308 (16.68%) male. The average age 49.92 years (Age range 19-87). final cytological diagnoses FNABs as follows: 287 (12.57%) nondiagnostic or unsatisfactory, 1517 (66.42%) benign cytology, 316 (13.83%) atypia undetermined significance/follicular lesion significance, 63 (2.75%) follicular neoplasm suspicious for a neoplasm, 59 (2.59%) malignancy 42 (1.84%) malignant cytology. Histologically, 245 (74.70%) benign, while 83 (25.30%) malignant. number true 216 (65.85%), 62 (19.90%), false 29 (8.84%) 21 (6.40%). case, accuracy rates, 74.7%, 88.16%, 84.76%, 68.13% 91.14%, respectively. Conclusion: our it observed that compatible literature. We think experience clinician cytopathologist increases, results will decrease at same time, confidence increase even more participation some recent molecular methods (BRAF RET/PTC, AX8/PPARG RAS) applied FNABs.